Search results for " tandem reactions."

showing 2 items of 2 documents

New approach to condensed pyrid-2-ones

2002

We wish to report a simple procedure for the preparation of 5-substituted-thienopyridin-7-ones and 7-substituted-1,6-naphthyridin-5(6H)-ones, in good yields, from the dianions of 3-methylthiophene-2-carboxylic and 2-methylnicotinic acids on treatment with nitriles. Brun Sanchez, Eva Maria, Eva.M.Brun@uv.es ; Gil Grau, Salvador, Salvador.Gil@uv.es ; Parra Alvarez, Margarita, Margarita.Parra@uv.es

ChemistryCarboxylic acidsUNESCO::QUÍMICAOrganic Chemistry:QUÍMICA::Química orgánica [UNESCO]HeterocyclesCombinatorial chemistry:QUÍMICA [UNESCO]Addition reactionslcsh:QD241-441lcsh:Organic chemistrySimple (abstract algebra)Computational chemistryNitrilesCarboxylic acids ; Nitriles ; Addition reactions ; Heterocycles ; Tandem reactionsTandem reactionsUNESCO::QUÍMICA::Química orgánica
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Synthesis of 4(5)-phenacyl-imidazoles from isoxazole side-chain rearrangements

2010

A novel base-induced rearrangement of isoxazoles into imidazole derivatives is reported. In the isoxazole series, this represents the first example of a three-atom side-chain rearrangement involving a CNC sequence. The reactions are carried out under nitrogen and produced 2-aryl-4(5)-phenacyl-5(4)-phenyl-imidazoles in high yields. In the presence of oxygen, a cascade rearrangement-oxidation reaction sequence was observed and imidazole derivatives bearing an oxidized side-chain were isolated.

Molecular StructureStereochemistryAcylationOrganic ChemistryImidazolesSequence (biology)Settore CHIM/06 - Chimica OrganicaIsoxazolesPhenacylBiochemistryHeterocyclic rearrangement isoxazole imidazole tandem reactions.Acylationchemistry.chemical_compoundReaction sequencechemistrySide chainImidazoleMoleculeIminesPhysical and Theoretical ChemistryIsoxazoleOxidation-ReductionOrg. Biomol. Chem.
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